Counterselection against Dμ Is Mediated through Immunoglobulin (Ig)α-Igβ
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چکیده
منابع مشابه
Counterselection against Dμ Is Mediated through Immunoglobulin (Ig)α-Igβ
The pre-B cell receptor is a key checkpoint regulator in developing B cells. Early events that are controlled by the pre-B cell receptor include positive selection for cells express membrane immunoglobulin heavy chains and negative selection against cells expressing truncated immunoglobulins that lack a complete variable region (D mu). Positive selection is known to be mediated by membrane immu...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1996
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.184.6.2079